Madam Therapeutics

National Alert System for Critical Antimicrobial Resistances: death rate as high as 50% for some bloodstream infections In Australia

The latest six-monthly report for the National Alert System for Critical Antimicrobial Resistance (CARAlert), released by the Australian Commission on Safety and Quality in Health Care, highlights the continuing threat of antimicrobial resistance by dangerous bacteria.

Carbapenemase-producing Enterobacteriaceae (also known as CPE) and Neisseria gonorrhoeae continue to be the most commonly reported organisms with critical resistances to antimicrobials across Australia, according to the report. CPE is a Gram-negative bacteria that is routinely encountered in hospitals and other healthcare facilities, while N. gonorrhoeae is a bacterial sexually transmitted infection.

“The finding that CPE remains prevalent in Australian hospitals is concerning,” said the Commission’s Senior Medical Advisor for the AURA Surveillance System, Professor John Turnidge. “This group of bacteria has the ability to cause common infections, has limited treatment options and can have a death rate as high as 50% for bloodstream infections.


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